摘要
视神经脊髓炎谱系疾病(NMOSD)是一组由自身免疫介导的中枢神经系统脱髓鞘疾病.越来越多的研究发现NMOSD患者即使没有临床症状,影像学上也会出现无症状病灶,包括无症状视神经病灶、无症状脊髓病灶及无症状脑部病灶.文中围绕NMOSD无症状病灶的特点、影响因素、与复发和残疾进展的关系以及处理策略等展开综述.
Abstract
Neuromyelitis optica spectrum disorders(NMOSD)are a group of autoimmune-mediated demyelinating diseases of the central nervous system.A growing number of studies have identified asymptomatic lesions on imaging in patients with NMOSD,including asymptomatic optic neuropathy,asymptomatic spinal lesions,and asymptomatic brain lesions,even in the absence of clinical symptoms.The characteristics of asymptomatic lesions of NMOSD,influencing factors,relationship with relapse and disability progression,and management strategies were reviewed in this article.
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