Analysis of the safety and efficacy of blood flow diverter in the treatment of intracranial ruptured aneurysm
Objective To explore the safety and efficacy of flow diverter(FD)in the treatment of patients with intracranial ruptured aneurysm.Methods The clinical data of 28 patients with intracranial ruptured aneurysms(28 aneurysms in total)treated with FD at the Department of Neurosurgery,the First Affiliated Hospital of Xinjiang Medical University from January 2019 to December 2021 were retrospectively analyzed.Among them,there were 8 males and 20 females;the age was 55.6±14.0 years old.Eighteen patients were treated with Pipeline embolization device(PED),and 10 patients were treated with Tubridge FD.Perioperative complications were recorded.All patients were hospitalized for digital subtraction angiography(DSA)examination 6 to 24 months after surgery,and the Kamran grade was used to evaluate the embolization of the aneurysm(Kamran grade 4 as complete embolization);the modified Rankin scale(mRS)to evaluate the patient's outcome(mRS of 0 to 2 points as good outcome).Results A total of 30 FD stents were used in 28 patients,of which 2 patients used 2 stents;19 patients were treated with combined coils.Among the 28 patients,6(21.4％)experienced perioperative complications,of which 5(17.8％)were hemorrhagic complications and 1(3.6％)were ischemic complications;the mortality rate was 7.1％(2/28).Among the 28 patients,25 were followed up,and the median follow-up time was 14(6 to 24)months.As of the last follow-up,1 case of aneurysm was Kamran grade 2,2 cases were grade 3,and 22 cases were grade 4.The aneurysm complete occlusion rate was 88.0％(22/25);21 cases had an mRS of 0 to 2,and 7 had an mRS of 3 to 6.For example,the good outcome rate was 75.0％(21/28).Conclusion As a method for the treatment of intracranial ruptured aneurysms,FD has a low perioperative complication rate and a high short-and medium-term aneurysm occlusion rate,and has good safety and effectiveness.
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