The influence of intraoperative ultrasound on surgical outcomes of patients with gliomas:a meta-analysis
Objective To systematically review the influence of intraoperative ultrasound on surgical outcomes of patients with gliomas.Methods PubMed,Embase,Cochrane Library,CNKI,VIP and WanFang databases were electronically searched to identify cohort studies investigating the influence of intraoperative ultrasound on surgical outcomes of patients with gliomas,which were published between January 1,2013 and December 31,2023.Two reviewers independently screened literatures,extracted data and assessed the risk of bias of included studies.Then meta-analysis was conducted using RevMan 5.4 software and Stata 16.0 software.The primary outcome measure was gross total resection(GTR)rate,and the secondary outcome measures were surgical duration and postoperative Karnofsky performance status score.The x2 test and I2 value were used to evaluate the heterogeneity between the results of included studies.In case of P＜0.05 or I2＞50％,the random effect model would be used to calculate the effect size.Otherwise,the fixed effect model would be used to calculate the effect size.Results A total of 17 cohort studies were included in the analysis,incorporating 1 364 glioma patients.The results of meta-analysis showed that compared with the conventional surgery group(634 cases),the intraoperative ultrasound group(730 cases)had a higher GTR rate(RR=1.52,95％CI:1.38-1.66,P＜0.001),a shorter surgical duration(SMD=-0.60,95％CI:-0.96--0.23,P=0.001),and a higher postoperative Kamofsky performance status score(SMD=0.76,95％CI:0.43-1.09,P＜0.001).Conclusion The use of intraoperative ultrasound can improve surgical outcomes and shorten surgical duration of patients with gliomas.
GliomaUltrasonographyMonitoring,intraoperativeNeurosurgical proceduresMeta-analysis as topic
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