Application of multimodal neuronavigation in thalamic glioma surgery
Objective To explore the effect of multimodal neuronavigation in thalamic glioma surgery.Methods A retrospective analysis was conducted on the clinical data of 53 patients with thalamic glioma admitted to the Department of Neurosurgery,the First Affiliated Hospital of Soochow University from January 2015 to January 2022.Among them,11 patients underwent routine operations(traditional surgical group),10 patients were treated with multimodal neuronavigation combined with intraoperative electrophysiological monitoring(combination technique group),and on the basis of the combined technology group,nuclear reconstruction technology were used in 32 cases to locate thalamic nuclei and brain functional areas before surgery(combination technique+preoperative positioning group).The differences in preoperative baseline condition,total tumor resection rate,operation time,new neurological deficits after surgery and the improvement of Karnofsky functional status score(KPS)at discharge were analyzed among the three groups.Results The total tumor resection rate of the traditional surgical group,the combination technique group and the combination technique+preoperative positioning group were 3/11,9/10 and 29/32(90.6％)respectively.The proportion of patients with new neurological deficits after surgery in the traditional surgical group,the combination technique group and the combination technique+preoperative positioning group were 6/11,1/10 and 5/32(15.6％)respectively.The proportion of patients with increased KPS score at discharge in the traditional surgical group,the combination technique group and the combination technique+preoperative positioning group were 1/11,6/10 and 18/32(56.3％)respectively.Compared with the traditional surgical group,both combination technique group and the combination technique+preoperative positioning group had significant differences in the above indicators(all P＜0.01).There were no statistically significant difference in the above indicators between the combination technique group and the combination technique+preoperative positioning group(all P＞0.05).There was no statistically significant difference in operation time among the three groups(P=0.930).Conclusion Using the multimodal neuronavigation in thalamic glioma surgery can improve the total tumor resection rate,reduce the neurological deficits and increase the KPS score after surgery.
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