Clinical characteristics of elderly patients with traumatic brain injury and factors influencing their mortality in Xinjiang region
Objective To summarize the clinical characteristics of elderly patients hospitalized with traumatic brain injury(TBI)in Xinjiang,and to explore the risk factors affecting patients'mortality.Methods A retrospective,multicenter study was conducted on the data of the clinical characteristics of elderly(≥65 years old)TBI inpatients in 28 hospitals of different levels in Xinjiang region from January 2021 to December 2021.We analyzed the clinical characteristics of elderly TBI inpatients in Xinjiang.Univariate analysis and multifactorial logistic regression analysis were used to explore the factors that might affect the mortality of patients.Results A total of 538 elderly TBI patients were included.The ratio of male to female was 2.02∶1.00 and the median age[M(Q1,Q3)]was 73(68,80)years old.Falling(59.85%,322/538)was the leading cause of injury in elder adults with TBI,followed by traffic injuries(30.11%,162/538).Subarachnoid hemorrhage(49.81%,268/538)was the most frequent type of intracranial injury,and 45.35%(244/538)of the patients had a combined extracranial injury.14.68%(79/538)of the patients exhibited midline shift.20.26%(109/538)of the patients were admitted to the intensive care unit.Conservative treatment was given to 78.81%(424/538)of the patients.The patient'mortality rate was 6.69%(36/538).The results of univariate analysis showed that Glasgow Coma Score,the occurrence of midline shift,the occurrence of emergency tracheal intubation,place of admission,and whether or not surgery was performed were associated with the patient'mortality(all P<0.05).The results of multifactorial logistic analysis showed that low Glasgow Coma Score on admission(OR=6.99,95%CI:1.80-27.13),midline shift(OR=4.95,95%CI:1.97-12.46),emergency endotracheal intubation(OR=5.92,95%CI:2.12-16.53),and being admitted to the intensive care unit(OR=6.41,95%CI:1.91-21.58),and performing surgery(OR=4.62,95%CI:1.54-13.84)were all independent risk factors for death in elderly TBI patients(all P<0.05).Conclusions Elderly TBI patients in Xinjiang region are predominantly males,the main cause of injury is falling on the ground,and the overall prognosis is good.Patients with a low Glasgow Coma Score on admission,midline shift,emergency tracheal intubation,immediate admission to the intensive care unit,and surgery seem to be at higher risk of death.
Brain injuries,traumaticDisease attributesAgedRoot cause analysis