首页|伽玛刀术后复发性三叉神经痛的显微外科手术疗效分析

伽玛刀术后复发性三叉神经痛的显微外科手术疗效分析

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目的 观察显微外科手术治疗伽玛刀术后复发性三叉神经痛(TN)的可行性及疗效.方法 回顾性分析2010年1月至2021年4月无锡市第二人民医院神经外科采用显微手术治疗的伽玛刀术后复发的原发性TN患者的临床资料,共19例.其中对首选行显微血管减压术(MVD)再行伽玛刀治疗的2例患者采用神经根梳理术;首选行伽玛刀治疗的17例患者中,4例单纯行MVD,13例行MVD+神经根梳理术.观察手术疗效及相关并发症.采用巴罗神经学研究所(BNI)疼痛强度评级评价疼痛缓解程度.结果 19例患者均成功手术.术后疼痛完全缓解14例,部分缓解4例,无效1例.其中部分缓解的3例和无效的1例患者均为单纯行MVD者.术后19例患者的随访时间为(63.9±13.9)个月(48~96个月).15例行MVD+神经根梳理术的患者中,随访期14例无复发,1例部分缓解者的疼痛程度无变化.4例单纯行MVD的患者,2例疼痛程度无明显变化,2例部分缓解者均在术后8个月复发.结论 采用显微外科手术治疗伽玛刀术后复发性TN技术可行,无严重的手术相关并发症.其中采用MVD+神经根梳理术的治疗方案能有效缓解疼痛症状,单纯采用MVD方案的患者疗效有限.
Efficacy observation of microscopic surgery in the treatment of recurrent trigeminal neuralgia after Gamma knife surgery
Objective To observe the feasibility and efficacy of microscopic surgery in treating recurrent trigeminal neuralgia(TN)after Gamma knife surgery.Methods A retrospective analysis was conducted on patients with recurrent TN who underwent microscopic surgery in the Neurosurgery Department of Wuxi Second People's Hospital from January 2010 to April 2021.Among the 19 patients included in the study,2 had initially received microvascular decompression(MVD)before undergoing nerve root decompression after Gamma knife treatment.Of the 17 patients primarily treated with Gamma knife surgery,4 underwent merely MVD,while 13 received MVD combined with nerve root decompression.The Barrow Neurological Institute(BNI)pain intensity score was utilized to evaluate the degree of pain relief,and surgical efficacy along with related complications were monitored.Results All 19 patients underwent successful surgery.During the perioperative period,14 patients achieved complete pain relief,4 experienced partial relief,and 1 had ineffective outcome.Among the patients with partial relief,3 had only undergone MVD.The average follow-up duration for the 19 patients was 63.9±13.9 months,ranging from 48 to 96 months.Among the 15 patients who underwent MVD combined with nerve root decompression,14 patients had no recurrence during the follow-up period,while 1 patient with partial relief experienced no change in the pain level.Of the 4 patients who underwent merely MVD,2 showed no significant changes,and both patients with partial relief experienced recurrence 8 months after surgery.Conclusions The use of microsurgical techniques to treat recurrent TN after Gamma knife surgery is feasible and associated with no serious surgery-related complications.The efficacy of patients who underwent only MVD is limited,and MVD combined with nerve root decompression could more effectively alleviate pain symptoms.

Trigeminal neuralgiaRecurrenceRadiosurgeryMicrosurgeryTreatment outcome

姬宇杰、曾海鑫、蔡铮、鲁晓杰、李江安、李兵

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无锡市第二人民医院神经外科,无锡 214002

三叉神经痛 复发 放射外科手术 显微外科手术 治疗结果

2024

中华神经外科杂志
中华医学会

中华神经外科杂志

CSTPCD北大核心
影响因子:1.107
ISSN:1001-2346
年,卷(期):2024.40(12)