首页|3D打印导板在经皮球囊压迫术治疗药物难治性原发性三叉神经痛中的作用

3D打印导板在经皮球囊压迫术治疗药物难治性原发性三叉神经痛中的作用

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目的 探讨3D打印导板在经皮球囊压迫术(PBC)治疗药物难治性原发性三叉神经痛(TN)中的作用.方法 回顾性收集2020年10月至2023年10月石河子大学第一附属医院神经外科采用PBC治疗的39例药物难治性原发性TN患者.其中16例患者选择采用3D打印导板辅助PBC穿刺卵圆孔(研究组);23例在数字减影血管造影引导下采用经典的Hartel路径行徒手穿刺卵圆孔(对照组).比较两组患者的卵圆孔穿刺次数、穿刺时长,总手术时长、对比剂使用剂量、球囊压迫时长、球囊形状呈"梨形"成功率、手术相关并发症的发生情况及术后巴罗神经学研究所(BNI)疼痛强度分级的差异.结果 39例患者均成功手术.与对照组比较,研究组的卵圆孔穿刺次数少[1(1,2)次对比 2(2,3)次]、穿刺时长[1.8(1.0,3.8)min对比 6.0(3.0,16.0)min]和总手术时长[(29.6±3.9)min对比(46.3±15.1)min]均短,差异均有统计学意义(均P<0.001);研究组与对照组的球囊形状呈"梨形"成功率分别为75.0%(12/16)、60.9%(14/23),差异无统计学意义(P=0.495),而球囊一次性呈"梨形"的成功率分别为62.5%(10/16)、13.0%(3/23),差异有统计学意义(P=0.002).两组患者术后均无严重并发症,除研究组发生穿刺点肿胀的比率低于对照组外[12.5%(2/16)对比56.5%(13/23),P=0.008)],两组发生面部麻木、咀嚼困难、疱疹比例的差异均无统计学意义(均P>0.05).术后3个月两组患者BNI疼痛强度分级的差异无统计学意义(P=0.922).结论 3D打印导板辅助PBC治疗药物难治性原发性TN,能有效提高卵圆孔的穿刺成功率、缩短手术时长、降低手术风险.
Role of 3D printed guide plate in percutaneous balloon compression for drug-refractory trigeminal neuralgia
Objective To explore the role of 3D printed guide plate in percutaneous balloon compression(PBC)for the treatment of medically refractory trigeminal neuralgia(TN).Methods Clinical data of 39 patients with drug-refractory TN treated with PBC from October 2020 to October 2023 at the Department of Neurosurgery of the First Affiliated Hospital of Shihezi University were retrospectively collected.Among them,16 patients chose to use 3D-printed guides to assist PBC(experimental group);23 patients refused to use 3D printed guides and were punctured with bare hands under digital subtraction angiography guidance(control group).The number of patent foramen ovale punctures,puncture time,total procedure duration,dose of contrast used,duration of balloon compression,pear shape formation of balloon,postoperative Barrow Neurological Institute(BNI)pain intensity score,and the occurrence of procedure-related complications were compared between the two groups.Results All 39 patients underwent successful operation.Compared with the control group,the study group had fewer intraoperative punctures of the foramen ovale[1(1,2)vs.2(2,3)],shorter puncture time[1.8(1.0,3.8)min vs.6.0(3.0,16.0)min],and shorter total operative time[29.6±3.9 min vs.46.3±15.1 min],and the differences were statistically significant(all P<0.001).The success rate of"pear-shaped"balloon[75.0%(12/16)vs.60.9%(14/23)]and the success rate of"pear-shaped"balloon at one time[62.5%(10/16)vs.13.0%(3/23)]were both higher.However,the difference in the success rate of"pear-shaped"balloon was not statistically significant(P=0.495),while the difference in the success rate of"pear-shaped"balloon at one time was statistically significant(P=0.002).There were no serious postoperative complications in either group,and the difference in the proportion of facial numbness,difficulty in mastication or herpes was not statistically significant in the study group except for the proportion of swelling at the puncture site,which was smaller than that in the control group[12.5%(2/16)vs.56.5%(13/23),P=0.008].The difference in the BNI score between the two groups at 3 months postoperatively was not statistically significant(P=0.922).Conclusion PBC assisted with 3D printed guide plate for drug-refractory TN can effectively improve the success rate of puncture,shorten the operation time and reduce the risk of surgery.

Trigeminal neuralgiaPercutaneous balloon compression3D printed guide plateTreatment outcome

王世龙、李君、王刚刚、董江涛、徐浩翔、朱立仓、许晖

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石河子大学第一附属医院神经外科,石河子 832000

石河子大学第一附属医院皮肤科,石河子 832000

三叉神经痛 经皮球囊压迫术 3D打印导板 治疗结果

2024

中华神经外科杂志
中华医学会

中华神经外科杂志

CSTPCD北大核心
影响因子:1.107
ISSN:1001-2346
年,卷(期):2024.40(12)