Research advances on the role of adipokines in diabetic peripheral arterial diseases
Peripheral arterial disease is one of the common complications of diabetes.At present,the pathogenesis of diabetic peripheral arterial diseases is not completely clear,and there is a lack of effective treatment methods and drugs.Adipokines have profound impact on the occurrence and development of diabetes mellitus and its complications,and are directly or indirectly involved in the progression of diabetic peripheral arterial diseases.Different adipokines may inhibit or promote the occurrence of vascular diseases with the mechanisms that are complex and controversial.Adipokines are expected to be a new target for the treatment of diabetic peripheral arterial disease,which is worthy of further study.This article mainly reviews the relationship between some common adipokines and new adipokines and diabetic vascular disease,aiming to provide new methods for the clinical treatment of diabetic peripheral arterial disease.