慢性放射性溃疡的诊疗策略
Diagnosis and treatment strategies of chronic radiation ulcers
沈余明 1胡云刚1
作者信息
- 1. 首都医科大学附属北京积水潭医院烧伤科,北京 100035
- 折叠
摘要
随着对肿瘤行放射治疗和各种介入治疗的增加,慢性放射性溃疡患者逐渐增多.慢性放射性溃疡多累及皮下深层,伴周围皮肤纤维化,溃疡迁延不愈,呈进行性、不可逆发展,常规换药、皮片移植难以取得良好疗效,严重影响患者生活质量.该文从慢性放射性溃疡发病机制、临床特点、病理变化、创面评估及修复策略等多个方面进行了系统论述,为慢性放射性溃疡的临床诊疗提供参考.
Abstract
With the increase of radiotherapy and various interventional therapies for tumor,the number of patients with chronic radiation ulcers is increasing gradually.Chronic radiation ulcers mostly involve the deep subcutaneous layers,accompanied by fibrosis of the surrounding skin.The ulcers persist and develop progressively and irreversibly.It is difficult to achieve good curative effects by routine dressing change and skin grafting,seriously affecting the patients'quality of life.This article systematically discusses the pathogenesis,clinical characteristics,pathological changes,wound assessment,and repair strategies of chronic radiation ulcers to provide a reference for the clinical diagnosis and treatment of chronic radiation ulcers.
关键词
放射疗法/皮肤溃疡/辐射损伤/清创术/肌皮瓣/诊疗模式Key words
Radiotherapy/Skin ulcer/Radiation injuries/Debridement/Myocutaneous flap/Practice patterns引用本文复制引用
基金项目
国家重点研发计划(2022YFC2403004)
出版年
2024
NETL
NSTL
万方数据