Research advances on the mechanism of circadian rhythm genes in wound healing
The healing after skin injury is a dynamic process of the interaction of various cells,cytokines,and extracellular matrix,and the abnormality of any link will affect the speed and quality of wound healing.Circadian rhythm is a spontaneous periodic oscillation cycle in organisms,which plays an important role in maintaining homeostasis and regulating physiological activities.Studies have shown that circadian rhythm genes play a key role in wound healing.This review summarizes the effects of circadian rhythm genes on different stages of wound healing and its possible mechanism of action,in order to provide a new perspective for wound healing and provide theoretical basis for formulating more effective treatment strategies for refractory wounds.
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