2023年上海市病毒性急性呼吸道感染监测结果分析
Analysis of viral infections in adult acute respiratory infection cases in Shanghai,2023
王环茹 1牟嘉斌 1邱琪 1刘嘉婧 1袁芳 1刘梅花 2唐小德 3张靖翊 1陈健 1陈敏 1吴寰宇 1滕峥1
作者信息
- 1. 上海市疾病预防控制中心,上海 200336
- 2. 上海市奉贤区疾病预防控制中心,上海 201499
- 3. 上海市宝山区疾病预防控制中心,上海 201901
- 折叠
摘要
目的 分析2023年上海市病毒性急性呼吸道感染的病原学特征和流行特点,为相关呼吸道疾病防控和风险评估提供科学依据.方法 基于2023年上海市急性呼吸道感染多病原监测工作,对哨点医院报送的临床监测标本进行呼吸道病原体多重PCR检测,结合标本信息对检出病例进行病原学与流行病学分析.结果 2023年度上海市病毒性急性呼吸道感染监测标本中病毒性病原体阳性检出率为21.17％(984/4 648),其中ILI病例标本的检出率为33.53％(504/1 503),严重急性呼吸道感染病例标本检出率为15.62％(480/3 145).甲型流感病毒(Flu A)的检出率最高(13.7％,637/4 648),其他病原体包括人偏肺病毒(HMPV)、人鼻病毒/肠道病毒(HRV/HEV)、呼吸道合胞病毒(RSV)、副流感病毒(PIV)、腺病毒(ADV)、乙型流感病毒(Flu B)和人博卡病毒(HBoV)均有检出.从时间分布看,HRV/HEV和RSV在第二季度检出率最高,均为2.27％(28/1 236),PIV在第三季度检出率最高,为2.49％(35/1 405),HMPV则主要在第三季度与第四季度流行,其检出率分别为2.63％(37/1 405)和2.35％(32/1 360).结论 Flu A为上海市市2023年度急性呼吸道感染监测病例中的主要呼吸道病原体,HMPV检出率仅次于Flu A,HRV/HEV、RSV、PIV等其他各类呼吸道病毒在不同季度均有检出且存在叠加流行,各种呼吸道病毒在不同感染人群和不同时间的流行情况存在差异.
Abstract
Objective To elucidate the etiological and epidemiological characteristics and epidemiological patterns of viral acute respiratory infections(ARI)in Shanghai during 2023,with the aim of providing robust laboratory evidence for effective prevention and control strategies against related respiratory diseases and facilitating risk assessment.Methods Respiratory pathogens were detected in the clinical surveillance specimens submitted by sentinel hospitals through multiplex PCR,as part of the multi-pathogen surveillance of acute respiratory infections in Shanghai during 2023.The obtained detection result were statistically analyzed in conjunction with sample information.Results The positive detection rate of viral pathogens in 2023 was 21.17％(984/4 648),with rates of 33.53％(504/1 503)observed in ILI cases and 15.62％(480/3 145)in SARI cases.Influenza A virus(FluA)was the predominant virus detected,accounting for 13.7％(637/4 648).Other viruses identified in the surveillance samples included influenza B virus(Flu B),human rhinovirus/enterovirus(HRV/HEV),respiratory syncytial virus(RSV),human metapneumovirus(HMPV),parainfluenza virus(PIV),adenovirus(ADV)and human bocavirus(HBoV).Regarding temporal distribution,HRV/HEV and RSV exhibited the highest detection rates during the second quarter at 2.27％each(28/1 236).PIV had its peak during the third quarter at a rate of 2.49％(35/1 405),and HMPV showed prevalence mainly during the third and fourth quarters,with detection rates of 2.63％(37/1 405)and 2.35％(32/1 360),respectively.Conclusions In acute respiratory infection surveillance cases in Shanghai in 2023,Flu A emerged as the predominant respiratory pathogen.The detection rate of HMPV ranked second only to Flu A,while other respiratory viruses such as HRV/HEV,RSV,and PIV were detected during different seasons and co-circulated.The prevalence of various respiratory viruses varied among different infected populations and over times.
关键词
急性呼吸道感染/呼吸道病毒/流感样病例/严重急性呼吸道感染Key words
Acute respiratory infection/Respiratory viruses/Influenza-like illness/Severe acute respiratory infections引用本文复制引用
基金项目
上海市加强公共卫生体系建设三年行动计划(2023-2025)(GWVI-3)
出版年
2024
NETL
NSTL
万方数据