摘要
抗病毒治疗是治愈慢性丙型肝炎(chronic hepatitis C,CHC)的有效手段,也是预防丙肝传播的重点.通过分析国内外文献,从CHC抗病毒治疗率的估计、国内外CHC抗病毒治疗情况及影响CHC接受抗病毒治疗的因素等方面进行概述.目前国内外CHC病例抗病毒治疗率较低,CHC病例接受治疗情况受病例的一般情况、知晓HCV核酸检测结果或自感病情程度、同时患有其他疾病或状态、丙肝防治知识知晓程度、社会交往和行为指导等影响.实现消除丙肝公共卫生危害的目标,提高慢性丙型肝炎抗病毒治疗率是重难点,相关因素有待深入研究.强化政策支持、提高丙肝确诊诊断、多病同防、针对性宣传教育、加强社会支持可有效提高慢性丙型肝炎抗病毒治疗率,助力实现消除丙肝公共卫生危害目标.
Abstract
Antiviral therapy is an effective means of curing chronic hepatitis C(CHC)and a key focus of preventing the spread of hepatitis C.By analyzing domestic and foreign literature,this paper provides an overview of the estimation of the antiviral treatment rate for CHC,the current situation of antiviral treatment for CHC both domestically and internationally,and the factors that affect acceptance of antiviral treatment.At present,the antiviral treatment rate for CHC cases is relatively low both domestically and internationally.The treatment status of CHC cases is related to factors such as the general situation of the case,knowing their HCV status or self-perceived condition,concurrent presence of other diseases or conditions,knowledge of hepatitis C prevention and treatment,and social interaction and behavioral guidance.In response to the relevant difficulties,in-depth research or more support is needed to improve the antiviral treatment rate of CHC cases and achieve the goal of eliminating hepatitis C by 2030.Efforts should be made to strengthen policy support,improve the diagnosis of hepatitis C,prevent and control multiple diseases together,conduct targeted publicity and education,and enhance social support.
维普
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