Objective To evaluate the relationship between blood flow in the bone and bone interal pressure.Methods Fifteen New Zealand white rabbits were made into the tibia bone hypertension model.The intraosseous pressure was measured before and after modeling.The infrared hot chart image formation technology and the isotope scanning method were used to examine the lesioned knee and the healthy knee image formation temperature and the radioactivity enrichment situation separately, and the differences were compared.Results The thermal imagery chart of the lesioned knee showed the knee joint as the central temperature increment chart.The temperature in the lesioned knee was (25.06 ± 0.67) and (25.17 ± 0.36) ℃, and radioactivity enrichment was (13.68 ± 2.89), which were significantly higher than the healthy knee [(23.89 ± 1.67), (24.65 ± 1.03) ℃, and (12.07 ± 1.86)] (P <0.05).Conclusion There was a positive relationship between the intraosseous pressure and distribution of blood flow.The infrared thermography imaging could be used to measure the distribution of intraosseous blood flow.