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经尿道前列腺电切术后膀胱颈挛缩的相关因素分析

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目的 探讨经尿道前列腺电切术(TURP)后膀胱颈挛缩(BNC)的相关因素.方法 收集2012年1月至2020年12月于徐州医科大学附属医院泌尿外科行TURP治疗的良性前列腺增生(BPH)患者的临床资料.根据患者术后是否发生膀胱颈口挛缩分为BNC组和非BNC组.运用Logistic回归模型进行单因素和多因素分析,筛选TURP后BNC发生的独立危险因素.结果 本研究共纳入451例BPH患者,中位随访时间25.3(14.1~104.0)个月,其中BNC组30例,非BNC组421例.单因素和多因素Logistic回归分析结果表明,前列腺体积≤50 ml[比值比(OR)=2.890,95%可信区间(CI):1.176~7.104,P<0.05],纤维蛋白原水平≤2.5 g/L(OR=2.246,95%CI:1.016~4.965,P<0.05)和术后留置尿管时间≥7 d(OR=2.850,95%CI:1.173~6.926,P<0.05)是 TURP后BNC发生的独立危险因素.结论 为减少TURP后BNC的发生,术前应测定纤维蛋白原水平;对于小体积前列腺,应严格把握手术适应证;术后患者尿色清时,应尽早拔除尿管.1年内要加强患者随访,早期诊断和治疗BNC,以提高患者的手术疗效和生活质量.
Analysis of related factors of bladder neck contracture after transurethral resection of prostate
Objective To explore the related factors of bladder neck contracture(BNC)after tran-surethral resection of the prostate(TURP).Methods The clinical data of patients with benign prostatic hyperplasia(BPH)who were treated with TURP in the Department of Urology in our Hospital from January 2012 to December 2020 were collected.According to the occurrence of BNC after operation,the patients were divided into BNC group and non-BNC group.Then univariate and multivariate analysis was carried out by Logistic regression model to screen the independent risk factors of BNC after TURP.Results A total of 451 patients with BPH were enrolled in this study.The median follow-up time was 25.3(14.1-104.0)months,including 30 patients in the BNC group and 421 patients in the non-BNC group.Univariate and Multivariate Logistic regression analysis showed that prostate volume≤50 ml[odds ratio(OR)=2.890,95%confidence interval(CI):1.176-7.104,P<0.05],fibrinogen level ≤2.5 g/L(OR=2.246,95%CI:1.016-4.965,P<0.05)and postoperative indwelling catheter time ≥ 7 days(OR=2.850,95%CI:1.173-6.926,P<0.05)were independent risk factors for BNC after TURP.Conclusion In order to re-duce the occurrence of BNC after TURP,the level of fibrinogen should be determined before operation,the indication of operation should be strictly grasped for small prostate,and the urinary catheter should be re-moved as soon as possible when the urine color is clear after operation.The follow-up,early diagnosis and treatment of BNC should be strengthened within one year,so as to improve the surgical effect and quality of life of the patients.

ProstateTransurethral resection of prostateBladder neck contractureFactors

许阳、施田力、江玉立、于冬冬、李望、李鹏

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湖州市中心医院(浙江中医药大学第五临床医学院)泌尿外科,湖州 313000

徐州医科大学附属医院泌尿外科,徐州 221002

前列腺 经尿道前列腺电切术 膀胱颈挛缩 因素

浙江省医学会临床科研基金项目

2022ZYC-A64

2024

中华实验外科杂志
中华医学会

中华实验外科杂志

CSTPCD
影响因子:0.759
ISSN:1001-9030
年,卷(期):2024.41(2)
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