Analysis of the correlation between hip function score and visual analogue scale score and inflam-matory factors in patients with hip bone defects
Objective To explore the correlation between hip function score and visual analogue scale score and inflammatory factors in patients with hip bone defects.Methods From May 2020 to May 2023,39 patients with hip bone defects were selected as the research objects.All patients underwent total hip revision surgery via the posterolateral approach.The levels of tumor necrosis factor-α(TNF-α),inter-leukin(IL)-1 β and IL-6 were measured by enzyme linked immunosorbent assay(ELISA)before and after operation.The hip function and subjective pain were analyzed by Harris hip function score and visual ana-logue scale.The correlation between the expression levels of TNF-α,IL-1β and IL-6 and Harris hip func-tion score and visual analogue scale score was analyzed by Pearson correlation coefficient.The t test was used for comparison of measurement data.Results The levels of TNF-α,IL-1 β and IL-6 before treatment[(83.28±12.40),(63.77±11.82),(101.23±17.35)ng/ml]were significantly higher than those after treatment[(33.59±9.20),(23.43±5.51),(30.89±8.26)ng/ml,t=20.100,19.310,22.850,P＜0.05].The Harris hip function score before treatment[(71.64±7.73)points]was significantly lower than that after treatment[(91.64±4.38)points,t=14.060,P＜0.05].The Harris hip function score before treatment[(5.97±1.14)points]was significantly lower than that after treatment[(2.97±1.09)points,t=11.920,P＜0.05].The Harris hip function score was negatively correlated with the levels of serum TNF-α,IL-1β and IL-6(r=-0.547,-0.716,-0.563,P＜0.05).The visual analogue scale score was positively correlated with the levels of serum TNF-α,IL-1β and IL-6(r=0.287,0.346,0.415,P＜0.05).Conclusion The levels of inflammatory factors in patients with hip bone defect after hip arthroplasty were significantly decreased,and the hip function and visual analogue scale score were sig-nificantly improved.The postoperative inflammatory factor levels were negatively correlated with the postop-erative hip function,and inversely proportional to the visual analogue scale score.
Hip bone defectHip arthroplastyVisual analogue scale scoreInflammatory factors
NETL
NSTL
万方数据
