中华实验外科杂志2024,Vol.41Issue(3) :646-649.DOI:10.3760/cma.j.cn421213-20230808-01292

干细胞治疗肌肉骨骼疾病的研究进展

Advances in stem cell therapy for musculoskeletal disorders

金文意 陈俊文 张宇标 彭昊
中华实验外科杂志2024,Vol.41Issue(3) :646-649.DOI:10.3760/cma.j.cn421213-20230808-01292

干细胞治疗肌肉骨骼疾病的研究进展

Advances in stem cell therapy for musculoskeletal disorders

金文意 1陈俊文 1张宇标 1彭昊1
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作者信息

  • 1. 武汉大学人民医院关节外科,武汉 430060
  • 折叠

摘要

肌肉骨骼疾病,包括股骨头坏死、骨关节炎等,是导致非致命性伤残的首要因素,因此,需要探索更为完善的治疗方案.目前,干细胞疗法,尤其是异体来源的脐带干细胞治疗策略,已被证实对各个肌肉骨骼疾病均具有显著治疗效果.本文综述当前MSCs治疗肌肉骨骼疾病的研究进展,以进一步促进干细胞疗法的临床应用.

Abstract

Musculoskeletal disorders,including femoral head necrosis and osteoarthritis,are the leading cause of non-fatal disability,and therefore more sophisticated treatment options need to be explored.Currently,mesenchymal stem cell therapies,especially the therapeutic strategy of allogeneic umbilical cord mesenchymal stem cells,have been shown to have significant therapeutic effects for various musculoskeletal disorders.This article summarizes the current research progress in MSC therapy for musculoskeletal disorders in order to further promote the clinical application of stem cell therapies.

关键词

干细胞/人脐带干细胞/股骨头坏死/骨关节炎

Key words

Stem cells/Human umbilical cord mesenchymal stem cells/Necrosis of femoral head/Ostc-oarthritis

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出版年

2024
中华实验外科杂志
中华医学会

中华实验外科杂志

CSTPCD
影响因子:0.759
ISSN:1001-9030
参考文献量31
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