Effect of early rehabilitation treatment on motor function,quality of life and related mechanism of prognosis after thrombolysis in cerebral infarction
Objective To explore the effect of early rehabilitation nursing on motor function,quality of life and the related mechanism of prognosis after thrombolysis in cerebral infarction.Methods Totally,80 patients with acute cerebral infarction admitted to our hospital from January to December of the 2021-2023 were selected.The patients were randomly divided into two groups:control group(n=40)and observation group(n=40),in which the patients in the control group were given routine nursing care,while those in the observation group were given postoperative rapid rehabilitation nursing and continuous nursing care.Serum malondialdehyde(MDA)and superoxide dismutase(SOD)served as the stress markers.The nursing effect,Fugl-Meter motor function score and brief health measurement scale were compared between the two groups.Independent sample t-test was used for inter group comparison,and chi square test was used for count data.Results The observation group had a higher clinical nursing efficacy rate than the control group[100.0％(40/40)vs.85.0％(34/40),x2=4.53,P＜0.05].After receiving rehabilitation nursing intervention,the motor function score(FMA)and quality of life score(SF-36)of the observation group were significantly high-er than those of the control group[(47.62±3.13),(41.36±3.41)points vs.(38.25±4.35),(36.25± 3.22)points,t=7.651,0.425,P＜0.05;(80.43±5.62),(68.65±4.58)points vs.(62.13±5.21),(98.32±4.60)points,t=6.824,0.289,P＜0.05].In the comparison of stress response indicators be-tween two groups of patients before and after receiving different nursing interventions,the observation group had significantly higher levels of malondialdehyde and oxide dismutase than the control group after interven-tion(6.25±0.89,5.51±0.57 vs.4.21±0.18,4.05±0.12,t=4.051,0.642,P＜0.05;84.03±2.68,79.15±3.50 vs.98.13±4.61,98.32±4.60),t=3.256,0.128,P＜0.01);Univariate regression analy-sis and multiple regression analysis(stepwise method)were used to analyze the incidence rate and risk fac-tors.Age ≥ 65 years old,neurological deficit score before thrombolysis ≥ 15 points,atrial fibrillation,bleeding after thrombolysis,time of thrombolysis ≥3 h,and blood glucose before thrombolysis ≥12.00 were independent risk factors affecting the prognosis of nursing and rehabilitation of patients with acute cerebral in-farction after intravenous thrombolysis[odds ratio(OR)＞1 and P＜0.05].Conclusion Early rehabilita-tion nursing has positive effect on motor function and quality of life after thrombolysis in cerebral infarction,and has definite effect on recovery of physiological function after thrombolysis in cerebral infarction.It is ben-eficial to improve the quality of life and prognosis of patients.
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