Research progress in macrophage surface low affinity immunoglobulin gamma Fc region receptor Ⅱ-B recep-tor mediated effects
The expression of low affinity immunoglobulin gamma Fc region receptor Ⅱ-B(FcγRⅡB)receptor on the surface of macrophages is correlated with inflammations,autoimmune diseases,tumors,organ transplantation,etc.The extensive immunological response induced by the binding of activated receptor FcγRs to antigen-antibody com-plexes,can be counteracted by the activation of FcγRⅡB.Regulating the expression of FcγRⅡB in macrophages can alleviate or treat inflammations,autoimmune diseases,tumors,organ transplant rejection,etc.
MacrophagesLow affinity immunoglobulin gamma Fc region receptor Ⅱ-BTreatment
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