Application of organoids in the treatment of colorectal cancer
Colorectal cancer organoids are 3D tumor cell models cultured in vitro with tumor tissues from pa-tients,which highly model the characteristics of tumor tissues and retain tumor heterogeneity between individuals.As a new preclinical model,organoid has made some progress in basic research,disease modeling,drug screening and development,overcoming the shortcomings of other models in medicine research.Here,we mainly review the applica-tion of organoids in the treatment of colorectal cancer,hoping to provide new strategies for the clinical treatment of colo-rectal cancer.
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