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胸外科基础研究的现状与展望

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目前肺癌的发病率和死亡率位居第一,国内食管癌患者人数占全世界一半以上,胸外科作为这两种疾病的诊治一线正面临前所未有的挑战。以手术为主,化疗、靶向治疗、免疫治疗为辅的治疗模式在不断的更新迭代,随着"空间单细胞多组学"、"更高层次的多模态"、"更深层次的学科交叉融合"等概念的出现,为胸外科的基础研究带来了机遇和挑战。我们胸外科医师应该在时代的潮流中,激流勇进,迎难而上,在基础研究领域深耕细作,促进基础向临床的转化,为胸外科的发展添砖加瓦。
The status quo and outlook of fundamental research in thoracic surgery
China currently has the highest number of esophageal cancer patients in the world,and lung cancer has the highest incidence and fatality rates globally.Thoracic surgery,being the primary meth-od for diagnosing and treating these conditions,faces unprecedented challenges.The surgical approach serves as the foundation of the treatment,continually evolving and improving with the integration of chemo-therapy,targeted therapy,and immunotherapy.The field of thoracic surgery's fundamental research en-counters both opportunities and challenges with the emergence of concepts such as"deeper interdisciplinary integration","spatial single-cell multi-omics",and"higher-level multi-modality".The Times emphasizes that thoracic surgeons must embrace risks and confront these challenges directly.Efforts should be dedica-ted to advancing basic research,facilitating the translation of research findings into clinical practice,and promoting the progress of the thoracic surgery profession.

Thoracic surgeryBasic researchThoracic tumor

刁明炘、武世豪、汪杨威、何世文、廖永德

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华中科技大学同济医学院附属协和医院胸外科,武汉 430022

胸外科 基础研究 胸部肿瘤

国家自然科学基金国家重点研发计划湖北省科技厅国际合作项目雄安新区科技创新专项希思科-豪森肿瘤研究基金武汉市科学技术局知识创新专项

820725932023YFC25086032023EHA0592023XAGG0071Y-HS202302-00512023020201010164

2024

中华实验外科杂志
中华医学会

中华实验外科杂志

CSTPCD
影响因子:0.759
ISSN:1001-9030
年,卷(期):2024.41(8)