Influencing factors and short-term prognosis of postoperative pulmonary complications in elderly patients with non-small cell lung cancer
Objective To explore the influencing factors and short-term prognosis of postoperative pulmonary complication(PPC)in elderly patients with non-small cell lung cancer(NSCLC).Methods Collect 150 elderly NSCLC patients who underwent thoracoscopic partial resection of the lung in our hospi-tal from August 2022 to June 2023,and divide them into PPC group(35 cases)and nPPC group(115 cases).Analyze the influencing factors of PPC.All selected patients underwent questionnaire sur-veys leicester cough questionnaire in mandarin Chinese version(LCQ-MC),simplified cough symptom score(sCSS),and modified medical research council(mMRC)before surgery,one week after discharge,and one month after discharge.Compare the relevant quality of life indicators between two groups of pa-tients and explore the differences in their short-term prognosis.Inter group comparison was analyzed using independent sample t-test,log rank,and Cox regression.Results The univariate analysis of PPC showed that body weight,gender,smoking history,forced vital capacity(FVC),history of diabetes,and operation mode were related to PPC in elderly NSCLC patients(x2=2.013,1.863,4.301,7.056,P＜0.05).Multivariate analysis showed that the mode of operation and the history of diabetes were the risk factors for PPC[odds ratio(OR)＞1,P＜0.05].One month after discharge,the LCQ-MC physiological,psychologi-cal,social,and overall scores of patients in the nPPC group were significantly higher than those in the PPC group[(5.90±1.04),(5.83±1.16),(6.02±0.99),(17.75±3.17)points vs.(5.46±0.78),(5.38±0.96),(5.62±0.78),(16.46±2.46)points,t=-2.680,-2.293,-2.470,-2.520,P＜0.05].One month after discharge,the sCSS daytime cough score and total cough score of patients in the nPPC group were significantly lower than those in the PPC group[(0.59±0.54),(1.01±1.01)points vs.(0.89±0.40),(1.51±0.89)points,t=3.461,2.658,P＜0.05].Conclusion The occur-rence of PPC in elderly NSCLC patients affects their short-term postoperative quality of life.The influencing factors of PPC cannot be ignored,and effective intervention measures should be taken in advance according to different influencing factors to reduce the incidence rate.
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