首页|神经调控治疗脑卒中后运动功能障碍研究的现状与展望

神经调控治疗脑卒中后运动功能障碍研究的现状与展望

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脑卒中具有发病率高、致残率高、死亡率高的特点,其后遗的运动功能障碍也是临床面临的重大挑战之一。对于脑卒中恢复期患者,尤其是那些经过康复治疗效果有限的患者,神经调控技术是一种新兴的治疗策略。其中,脑深部电刺激可通过调控大脑的特定区域来促进神经可塑性,改善患者的运动功能。而脊髓电刺激和迷走神经电刺激等神经调控技术因其安全性和有效性而逐渐受到重视。本文综合最新神经调控技术的研究现状,旨在深入探讨神经调控技术在脑卒中治疗中的应用机制,以及其在未来脑卒中康复和治疗中的潜在发展方向和应用前景。
Current status and prospects of neuromodulation therapy for motor dysfunction after stroke
Stroke is characterized by a high rate of incidence,disability,and mortality,with resid-ual motor dysfunction post-stroke being one of the significant clinical challenges.For stroke patients in the recovery phase,particularly those with limited outcomes from rehabilitation treatments,neuromodulation techniques have emerged as a novel therapeutic strategy.Deep brain stimulation can enhance neuroplastici-ty by modulating specific brain regions,which in turn can improve patients'motor functions.Neuromodula-tion approaches such as spinal cord stimulation and vagus nerve stimulation are increasingly recognized for their safety and effectiveness.This paper reviews the current state of neuromodulation technologies,aiming to delve into the mechanisms by which these techniques are applied in stroke treatment,as well as their potential future directions and prospects for application in stroke recovery and therapy.

NeuromodulationStrokeDeep brain stimulationVagus nerve stimulationSpinal cord stimulation

郑泽忠、韩春雷、孟凡刚

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首都医科大学,北京市神经外科研究所,北京 100070

首都医科大学附属北京天坛医院神经外科,北京 100070

神经电刺激研究与治疗北京市重点实验室,北京 100070

北京脑科学与类脑研究中心,北京 102206

郑州大学第一附属医院神经外科,郑州 450052

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神经调控 脑卒中 深部脑刺激 迷走神经电刺激 脊髓电刺激

2024

中华实验外科杂志
中华医学会

中华实验外科杂志

CSTPCD
影响因子:0.759
ISSN:1001-9030
年,卷(期):2024.41(9)