Progress in the effects of hypertension and antihypertensive drugs on osteoarthritis
Osteoarthritis(OA)is one of the most common chronic diseases of the joints,with a high preva-lence in the elderly population,and is a major cause of chronic pain,dysfunction and poor quality of life.Hypertension is a common complication in patients with OA and a major modifiable risk factor for cardiovascular events.The rela-tionship between hypertension and OA has received increasing attention.However,hypertension has been reported to negatively affect symptoms and quality of life in patients with OA.There are currently six main classes of drugs used to treat hypertension.These six classes of drugs have significant effects on the progression and symptoms of OA through different mechanisms.Therefore,it is critical to select appropriate medications for patients with hypertension combined with OA.In this article,we visualize and analyze articles related to hypertension and OA,and provide a review of the relationship between hypertension and OA and the effects of these six classes of antihypertensive drugs on OA,with the aim of providing guidance and reference for the clinical treatment of patients with hypertension combined with OA.