Advances in clinical and mechanism of disuse osteoporosis
Disuse osteoporosis is a type of secondary osteoporosis.Clinically,various diseases re-quire immobilization or weightlessness(aviation,aerospace,etc.),or insufficient physical activity of indi-vidual limbs or even complete disuse are risk factors for the occurrence and development of this disease.It may lead to a series of complications related to disuse osteoporosis,such as rapid bone loss,complex re-gional pain syndrome,soft tissue ossification around the joint(ectopic ossification),limb deformities and pathological fractures,which seriously affect the recovery and daily life of patients.At present,with the development of the pathogenesis of osteoporosis and clinical treatment drugs,disuse osteoporosis has attrac-ted more and more attention.This paper reviews the recent progress of clinical epidemiology,the clinical manifestations of different types of disuse osteoporosis,bone metabolism and the evaluation methods,as well as the pathogenesis.In order to explore the causes of disuse osteoporosis,pathogenesis and effective prevention and treatment method.
NETL
NSTL
万方数据
