脑胶质瘤肿瘤电场治疗的作用机制研究进展与展望
Research progress and prospect of the mechanism of Tumor treating fields for glioma
宋锶昀 1要马可 2段虎斌3
作者信息
- 1. 山西医科大学第一临床医学院临床医学系,太原 030001
- 2. 山西医科大学第三临床医学院临床医学系,太原 030032
- 3. 山西医科大学第一医院神经外科,太原 030001
- 折叠
摘要
肿瘤电场治疗(TTFields)是一种利用低强度、中频交变电场对抗癌症的非侵入性方法.1992年,Grosse和Schwan发现低强度交变电场在球形细胞中有诱发跨膜电压的能力,此后低强度交变电场因其在抑制肿瘤生长和进展方面的治疗潜力而受到关注.本文综述了 TTFields治疗胶质母细胞瘤(GBM)的机制和最近的研究进展,并分析了 TTFields的未来方向.
Abstract
Tumor Treating Fields is a non-invasive method that uses low-intensity,medium-frequency alterna-ting electric fields to fight cancer.In 1992,Grosse and Schwan discovered that low-intensity alternating electric fields have the ability to induce transmembrane voltages in spherical cells,and since then low-intensity alternating electric fields have attracted attention for their therapeutic potential in inhibiting tumor growth and progression.This article re-views the mechanism and recent research progress of TTFields in the treatment of glioblastoma,and analyzes the future direction of TTFields.
关键词
肿瘤电场治疗/胶质母细胞瘤/作用机制Key words
Tumor treating fields/Glioblastoma/Mechanism of action引用本文复制引用
出版年
2024
NETL
NSTL
万方数据