Objective To investigate the clinical effect of total mesorectal excision with preserva-tion of left colic artery(LCA)in the treatment of middle and low rectal cancer.Methods The study sub-jects were 76 patients with middle and low rectal cancer who received related treatment in the People's Hospital of Yangxin County from August 2022 to August 2023.The patients were divided into the control group(38 cases)and the study group(38 cases)by random number table method.The control group did not retain LCA during laparoscopic total mesorectal excision,and the study group retained LCA during ab-dominal total mesorectal excision.The levels of inflammatory factors,surgical indicators,probability of complications and gastrointestinal function indicators were compared between the two groups.Chi-square test and independent sample t test were used for statistical data analysis.Results The level of IL-8 in the study group was lower than that in the control group(54.38 pg/ml vs.72.09 pg/ml,t=9.67,P＜0.05),and the level of IL-6 in the study group was lower than that in the control group(34.51 ng/ml vs.62.19 ng/ml,t=8.78,P＜0.05).The intraoperative blood loss in the study group was lower than that in the control group(53.29 ml vs.61.37 ml,t=2.021,P＜0.05),the marginal arterial arch pressure in the study group was higher than that in the control group(42.09 mmHg vs.33.29 mmHg,t=10.669,P＜0.05),and the postoperative ventilation time in the study group was lower than that in the control group(1.98 d vs.2.91 d,t=5.831,P＜0.05),and the distance from anastomosis to anal verge in the study group was higher than that in the control group(5.05 cm vs.4.79 cm,t=2.624,P＜0.05).The incidence of complications in the study group was lower than that in the control group(2.63％vs.21.05％,x2=6.175,P＜0.05).MTL in the study group was higher than that in the control group at 7 days after operation(130.65 ng/L vs.125.29 ng/L,t=2.045,P＜0.05),GAS in the study group was higher than that in the control group(75.24 ng/L vs.70.08 ng/L,t=4.823,P＜0.05).Conclusion In the treatment of patients with middle and low rectal cancer undergoing laparoscopic total mesorectal exci-sion,the choice of retaining LCA can achieve ideal results.It can not only effectively control the inflamma-tory symptoms of patients,but also further optimize the surgical indicators of patients.It plays an effective preventive role in the occurrence of complications,with good safety.
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