椎体成形术后椎体再发骨折的临床研究
A Clinical Study on Recurrent Vertebral Fractures Following Vertebroplasty
凌华光 1朱宇 1李毅 1李高磊 1樊晓韩 1卢文龙 1黎少言 1梁龙博 1王航 1司苗呈1
作者信息
- 1. 郑州大学第二附属医院骨科二病区,郑州 450000
- 折叠
摘要
目的 探讨骨质疏松性椎体压缩骨折(OVCF)患者在椎体成形术(PVP)后发生邻近椎体骨折(AVF)和远端椎体骨折(RVF)的倾向性及再发时间,为术后预防椎体再骨折提供指导意见.方法 回顾性收集并分析于郑州大学第二附属医院从2021年9月至2023年11月确诊为OVCF经PVP治疗后椎体再发骨折的患者的临床及影像学资料共61例,按再发骨折类型分为AVF组和RVF组,对比可能影响两组患者的骨折再发风险的因素及发生时间的差异.计量资料根据正态性选择独立样本t检验和Man-Whitney U检验,计数资料采用x2检验.结果 两组患者的骨密度(BMD)T值与其再骨折发生率存在相关性(x2=31.24,P＜0.01),15例AVF的发生时间中位数为5.00(4.00,6.00)个月,46例RVF的发生时间中位数为10.50(7.00,17.25)个月,两组总体发生时间分布差异有统计学意义(Z=-4.20,P＜0.01).结论 骨密度越低,患者越易发生AVF,骨密度较高或中等更可能发生RVF,AVF的发生时间中位数明显早于RVF.
Abstract
Objective To explore the propensity for adjacent vertebral fractures(AVF)and remote vertebral fractures(RVF)following percutaneous vertebroplasty(PVP)in patients with osteoporotic verte-bral compression fractures(OVCF),and to determine the timing of recurrent fractures,in order to provide guidance for the prevention ofsubsequent vertebral fractures after surgery.Methods A retrospective anal-ysis was conducted on the clinical and radiological data of 61 patients with OVCF who underwent PVP and subsequently experienced refracture at the Second Affiliated Hospital of Zhengzhou University from Septem-ber 2021 to Noermber 2023.Patients were categorized into AVF and RVF groups to compare the risk fac-tors associated with refracture development and the time of occurrence of the re-fracture.Quantitative data were analyzed using independent samples t-tests and Mann-Whitney U tests based on normality,while count data were analyzed using chi-square tests.Results A correlation was observed between bone mineral den-sity(BMD)T-scores and the incidence of refracture(x2=31.24,P＜0.01).The median time to occur-rence for 15 cases of AVF was 5.00(4.00,6.00)months,while for 46 cases of RVF it was 10.50(7.00,17.25)months.The overall distribution of occurrence times between the two groups showed a statistically significant difference(Z=-4.20,P＜0.01).Conclusion Patients with lower BMD are more prone to AVF,while those with higher or moderate BMD are more likely to experience RVF.The median time to oc-currence of AVF is significantly earlier than that of RVF.
关键词
椎体成形术/椎体再发骨折/邻近椎体骨折/远端椎体骨折Key words
Vertebroplasty/Recurrent vertebral fractures/Adjacent vertebral fractures/Re-mote vertebral fracture引用本文复制引用
出版年
2024
NETL
NSTL
万方数据