A Clinical Study on Recurrent Vertebral Fractures Following Vertebroplasty
Objective To explore the propensity for adjacent vertebral fractures(AVF)and remote vertebral fractures(RVF)following percutaneous vertebroplasty(PVP)in patients with osteoporotic verte-bral compression fractures(OVCF),and to determine the timing of recurrent fractures,in order to provide guidance for the prevention ofsubsequent vertebral fractures after surgery.Methods A retrospective anal-ysis was conducted on the clinical and radiological data of 61 patients with OVCF who underwent PVP and subsequently experienced refracture at the Second Affiliated Hospital of Zhengzhou University from Septem-ber 2021 to Noermber 2023.Patients were categorized into AVF and RVF groups to compare the risk fac-tors associated with refracture development and the time of occurrence of the re-fracture.Quantitative data were analyzed using independent samples t-tests and Mann-Whitney U tests based on normality,while count data were analyzed using chi-square tests.Results A correlation was observed between bone mineral den-sity(BMD)T-scores and the incidence of refracture(x2=31.24,P<0.01).The median time to occur-rence for 15 cases of AVF was 5.00(4.00,6.00)months,while for 46 cases of RVF it was 10.50(7.00,17.25)months.The overall distribution of occurrence times between the two groups showed a statistically significant difference(Z=-4.20,P<0.01).Conclusion Patients with lower BMD are more prone to AVF,while those with higher or moderate BMD are more likely to experience RVF.The median time to oc-currence of AVF is significantly earlier than that of RVF.