Research progress of circular non-coding RNA in the mechanism of gastric cancer occurrence and development
Gastric cancer(GC)is a common malignant cancer that has always been a difficult problem in clini-cal and scientific research fields.CircRNAs are a class of closed circular non-coding RNA molecules that can mediate gene expression during epigenetic,transcriptional,and RNA regulation stages.In recent years,research has found that abnormal expression of some circular RNAs(circRNAs)is closely related to the occurrence and development of gastric cancer,and can be used as diagnostic biomarkers and therapeutic targets,with great research prospects.