硫代硫酸钠治疗维持性腹膜透析合并转移性肺钙化1例
Sodium thiosulfate treatment for maintenance peritoneal dialysis with metastatic pulmonary calcification:a case report
李丹丹 1包婷 1王瑞峰 1刘桂凌 1萧健萍 1徐璐 1王德光1
作者信息
- 1. 安徽医科大学第二附属医院肾脏内科,合肥 230601
- 折叠
摘要
转移性肺钙化(metastatic pulmonary calcification,MPC)是由钙盐在正常肺组织中异常沉积所致,好发于慢性肾衰竭患者.该文报道1例维持性腹膜透析患者出现肺部快速进展性病变病例,经锝-99m-亚甲基二磷酸钠全身骨扫描以及经皮肺穿刺病理检查确诊为MPC.经硫代硫酸钠静脉输注加非含钙磷结合剂治疗后,患者肺部钙化范围较治疗前明显缩小.停用硫代硫酸钠后,肺部病变未见进展.提示硫代硫酸钠联合非含钙磷结合剂治疗MPC有效.
Abstract
Metastatic pulmonary calcification(MPC),defined as abnormal deposition of calcium salts in the intact lung,is common in patients with chronic renal failure.The paper reported a case of rapidly progressing lung lesions in a maintenance peritoneal dialysis patient.The patient was finally diagnosed with MPC through 99Tcm-methylene diphosphonate bone scintigraphy and percutaneous lung puncture pathology.After treatment with intravenous infusion of sodium thiosulfate combined with a calcium-free phosphorus binding agents,the extent of pulmonary calcification decreased significantly compared to before.Pulmonary lesions did not progress after discontinuation of sodium thiosulfate.It suggests that sodium thiosulfate combined with calcium-free phosphorus binding agents is effective in treating MPC.
关键词
肺疾病/肾疾病/腹膜透析/转移性肺钙化/硫代硫酸钠Key words
Lung diseases/Kidney diseases/Peritoneal dialysis/Metastatic pulmonary calcification/Sodium thiosulfate引用本文复制引用
出版年
2024
NETL
NSTL
万方数据