伴高乳酸血症连续性肾替代治疗患者应用局部枸橼酸抗凝的研究进展
Researches progress on the application of regional citrate anticoagulation in continuous renal replacement therapy patients with hyperlactatemia
郑燚 1孙献坤 2王芳 2张凌 2王艳艳3
作者信息
- 1. 四川大学华西医院肾脏内科,成都 610041;四川大学华西医院护理学院,成都 610041
- 2. 四川大学华西医院肾脏内科,成都 610041
- 3. 四川大学华西医院护理学院,成都 610041;四川大学华西医院科技部,成都 610041
- 折叠
摘要
连续性肾替代治疗(continuous renal replacement therapy,CRRT)被广泛应用于各类急危重症患者,有效抗凝是开展CRRT的关键一步.局部枸橼酸抗凝(regional citrate anticoagulation,RCA)可降低患者出血风险,已广泛应用于临床.然而,RCA能否应用于伴高乳酸血症CRRT患者,尚存在争议.因此,笔者查阅国内外相关文献,就RCA在不同病因伴高乳酸血症CRRT患者中的应用进行综述,为临床RCA的应用提供参考和依据.
Abstract
Continuous renal replacement therapy(CRRT)is widely used in critically ill patients,and effective anticoagulation is a crucial step in this implementation.Regional citrate anticoagulation(RCA)has been widely used in clinical practice to reduce the risk of bleeding in patients.However,controversies persist regarding its application in CRRT patients with hyperlactatemia.Therefore,the author reviewed the progress in the application of RCA during CRRT in patients with hyperlactatemia of different etiologies by summarizing recent relevant literature,to provide a valuable reference and guide for its clinical implementation.
关键词
高乳酸血症/连续性肾替代疗法/抗凝药/局部枸橼酸抗凝Key words
Hyperlactatemia/Continuous renal replacement therapy/Anticoagulants/Regional citrate anticoagulation引用本文复制引用
基金项目
国家自然科学基金(82270106)
国家重点研发计划(2018YFC2001802-1)
四川省科技厅国际科技创新合作项目(2022YFH0074)
出版年
2024
NETL
NSTL
万方数据