肾窦异位脂肪沉积对肾损伤影响的研究进展
Research progress of ectopic fat deposition in renal sinus affecting renal injury
王莎莎 1韩甲 1刘向云2
作者信息
- 1. 上海健康医学院康复学院,上海 201318
- 2. 上海体育大学运动健康学院,上海 200438
- 折叠
摘要
异位脂肪沉积越来越被重视,尤其是具有局部效应的肝脏、心脏脂肪被研究较多,但是目前对肾窦异位脂肪沉积的研究较少.肾窦异位脂肪沉积增多对肾脏损害具有独立作用,但是其作用机制尚未清楚.本文将结合目前的研究从肾窦异位脂肪沉积相关影像学诊断、影响肾脏损伤的可能机制(肾窦异位脂肪沉积产生的机械性压力、脂毒性)以及目前对肾窦异位脂肪沉积的干预进行综述,以期研究者更多关注肾窦异位脂肪沉积在肾脏相关疾病发生、发展中的作用及其影响因素.
Abstract
The increasing focus and research on ectopic fat deposition,especially the locally impactful liver and cardiac fat,have been extensively studied.However,there has been relatively less research on renal sinus fat.The increased ectopic deposition of renal sinus fat has an independent effect on renal damage,but the underlying mechanism remains unclear.Therefore,this article will integrate current research to provide a comprehensive review of renal sinus ectopic fat deposition,covering its related imaging diagnosis,potential mechanisms influencing renal damage(mechanical pressure generated by renal sinus fat,lipotoxicity),and current interventions for renal sinus ectopic fat deposition.This is aimed at attracting more attention in clinical research to the role of renal sinus ectopic fat deposition in the occurrence and development of kidney-related diseases.
关键词
肥胖症/肾窦/异位脂肪沉积/机械压迫/脂毒性Key words
Obesity/Renal sinus/Ectopic fat deposition/Mechanical compression/Lipotoxicity引用本文复制引用
基金项目
上海健康医学院校级科研基金(SSF-24-03-01)
出版年
2024
NETL
NSTL
万方数据