摘要
肝内胆管癌是肝脏第二大原发性恶性肿瘤,近年来,肝内胆管癌的诊断和治疗虽然发展迅速,但患者的长期预后普遍较差。本文就目前已知的肝内胆管癌预后因素进行综述,其中包括:基因、蛋白分子、病理特征、临床参数、风险模型或诺模图、TNM分期系统等,以期准确的预测单个患者的生存、优化患者的治疗策略和实施个性化医疗、最终改善患者的生存和生活质量。
Abstract
Intrahepatic cholangiocarcinoma (ICC) is the second most common primary malignant tumor of the liver, in recent years, although the diagnosis and treatment of ICC have developed rapidly, the prognosis of these patients is still very poor. This article reviews the known prognostic factors of ICC, including: genes, protein molecules, pathological features, clinical parameters, risk model or normogram, TNM staging system and so on, in order to accurately predict the prognosis of individual patients, optimize the treatment strategy and implement personalized medicine, and ultimately improve the survival and life quality of patients.