目的 观察冷却对振动引起的人手指感觉神经动作电位(SNAP)波幅的影响。 方法 采用自身配对设计，随机选取15名健康成年人，利用冰袋将中指皮肤温度冷却至22℃左右，或保持常温(中指皮肤温度32℃左右)，将振动器置于受试者中指掌指关节处，施加振动，振动幅度2 mm，频率60 Hz。分别于振动前、振动时、振动停止后，采用电生理感觉神经传导检查记录受试者中指SNAP的波幅。 结果 相同温度条件下，振动时的中指SNAP波幅均较振动前低(P<0.05)，在振动停止后即刻恢复至振动前水平，振动前与振动停止后中指SNAP波幅比较，差异无统计学意义(P>0.05)。与32℃条件下同振动时间点比较，受试者在22℃条件下的中指SNAP波幅较高(P<0.05)。受试者32℃条件下的中指SNAP波幅差为(61.7±15.1)%，22℃条件下的波幅差为(24.1±7.0)%，与32℃条件下相比，受试者22℃条件下的中指SNAP波幅差值较小(P<0.05)。 结论 冷却能显著减少振动对人手指SNAP波幅降低的影响，这可能是冷却疗法治疗手-臂振动综合征的潜在机制之一。 Objective To observe any effect of cooling on the amplitude of vibration-induced sensory nerve action potentials (SNAPs) in human digits. Methods The middle fingers of 15 healthy adults were either cooled to about 22℃ using an ice pack or kept at about 32℃. A vibrator was applied to the joint connecting the middle finger and the palm vibrating with an amplitude of 2mm at a frequency of 60Hz. The amplitudes of middle finger SNAPs before, during and right after the vibration were recorded. Results The SNAP amplitude at a given temperature was lower during vibration than before it, but it immediately returned to the pre-vibration level after the vibration ceased. The middle finger SNAP amplitudes at 22℃ were significantly higher than those at 32℃ throughout. The decrease in amplitude at 32℃ (61.7±15.1%) was significantly greater than that at 22℃ (24.1±7.0%). Conclusions Cooling significantly reduces the effect of vibration on the amplitude of digital SNAPs. That suggests a way to protect the sensory nerves in hand-arm vibration syndrome.
Effects of cooling on the amplitude of vibration-induced sensory nerve action potentials
Objective To observe any effect of cooling on the amplitude of vibration-induced sensory nerve action potentials (SNAPs) in human digits. Methods The middle fingers of 15 healthy adults were either cooled to about 22℃ using an ice pack or kept at about 32℃. A vibrator was applied to the joint connecting the middle finger and the palm vibrating with an amplitude of 2mm at a frequency of 60Hz. The amplitudes of middle finger SNAPs before, during and right after the vibration were recorded. Results The SNAP amplitude at a given temperature was lower during vibration than before it, but it immediately returned to the pre-vibration level after the vibration ceased. The middle finger SNAP amplitudes at 22℃ were significantly higher than those at 32℃ throughout. The decrease in amplitude at 32℃ (61.7±15.1%) was significantly greater than that at 22℃ (24.1±7.0%). Conclusions Cooling significantly reduces the effect of vibration on the amplitude of digital SNAPs. That suggests a way to protect the sensory nerves in hand-arm vibration syndrome.
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