Objective To explore the intervention of norovirus epidemic in schools without suspending classes through health education by equipping vomiting bags.Methods A cluster randomized controlled trial was designed,and the schools with norovirus outbreaks in the jurisdiction were divided into intervention group and control group by cluster random sampling.After the epidemic ended,the epidemic rate,incidence rate,second-generation case recurrence rate,epidemic duration,school suspension rate and other relevant indicators were collected between the two groups,and the differences in prevention and control effects between the two groups were compared.SPSS 27.0 software was used for statistical analysis.The t-test was used to analyze continuous variables,and the Chi-square test or Fisher's exact test was used to analyze categorical variables.Results A total of 5 schools were included in the intervention group,with 673 subjects and 14 cases of norovirus infection.The incidence rate was 2.08%,the epidemic-related rate was 18.67%,the second-generation case recurrence rate was 1.35%,the number of days the epidemic lasted(8.40±1.67)days,and the school suspension rate was 0.The control group included 9 schools,605 participants,and 136 cases of norovirus.The incidence rate was 22.48%,the epidemic-related rate was 21.21%,the second-generation case recurrence rate was 21.18%,the number of days the epidemic lasted(7.89±1.69)days,and the school suspension rate was 92.86%.There was a statistically significant difference in the incidence rate between the two groups(x2=127.97,P<0.01),no significant difference in the epidemic-related rate(x2=0.143,P>0.05),and a statistically significant difference in the secondary incidence rate of the second-generation cases(x2=129.62,P<0.01).There was no significant difference in the number of days of the epidemic between the two groups(t=0.544,P>0.05).Conclusion The use of vomiting bags in schools can not stop classes and effectively reduce the rate of norovirus infection and the rate of secondary infection,which is of great significance for epidemic prevention and control.