首页|COVID-19感染患者低钾血症与临床预后的相关性研究

COVID-19感染患者低钾血症与临床预后的相关性研究

Correlation betweenhypokalemia and clinical prognosis in patients with COVID-19 infection

扫码查看
目的:评估轻型和中型2019新型冠状病毒病(COVID-19)感染患者低钾血症与临床预后之间的关系。方法:回顾性分析2021年8月4日至25日在扬州市第三人民医院住院治疗的125例非ICU收治的轻型及中型COVID-19感染患者,其中男性50例,女性75例;年龄18~87岁,平均(50.55±19.07)岁,研究低钾血症与其预后的相关性。结果:纳入研究的患者血钾水平波动在2.71~4.70 mmol/L。125例住院患者中有55例(44.00%)出现低钾血症。低钾血症患者核酸转阴时间及住院时间明显延长,ICU转入风险显著增高。相关性分析表明,血钾水平与核酸转阴时间和住院时间呈负相关。双变量logistic回归分析表明,低钾血症是轻型和中型COVID-19感染患者核酸转阴时间延长、住院时间延长及ICU转入风险增高的危险因素。结论:轻型和中型COVID-19感染患者普遍存在低钾血症,且低钾血症与住院时间延长有关。
Objective:To evaluate the relationship between hypokalemia and clinical outcomes in patients with mild and moderate COVID-19 infection.Methods:A total of 125 patients with mild and moderate COVID-19 infection who were not admitted to the Intensive Care Unit (ICU), the Third People’s Hospital of Yangzhou from 4 to 25 August 2021 were selected, including 50 males and 75 females. The mean age was (50.55±19.07) years. A retrospective analysis was performed to study the correlation between hypokalemia and prognosis.Results:The blood potassium levels of the included patients fluctuated between 2.71 and 4.70 mmol/L. Among 125 hospitalized patients, 55(44.00%) developed hypokalemia. The negative time of nucleic acid and the length of hospital stay were significantly prolonged in patients with hypokalemia, and the risk of ICU transfer was significantly increased. Correlation analysis showed that blood potassium level was negatively correlated with the time of negative nucleic acid conversion and the length of hospital stay. Bivariate logistic regression analysis showed that hypokalemia was a risk factor for prolonged negative nucleic acid conversion, prolonged hospital stay, and increased risk of ICU transfer in patients with mild and moderate COVID-19 infection.Conclusion:Hypokalemia is commonly found in patients with mild and moderate COVID-19 infection, and it is associated with prolonged hospital stay.

尹江涛、王宇超、潘鑫、缪志龙、梅琼、黄自强、刘大东

展开 >

212001 江苏镇江,江苏大学附属医院重症医学科;212001 江苏镇江,江苏大学消化病研究院

212001 江苏镇江,江苏大学医学院

212003 江苏镇江,镇江市急救中心急救科

212001 江苏镇江,镇江市中医院重症医学科

225100 江苏扬州,扬州市第三人民医院感染科

212001 江苏镇江,江苏大学附属医院重症医学科;210018 江苏南京,中国人民解放军东部战区总医院

展开 >

新冠病毒感染 低钾血症 核酸转阴时间 住院时间 ICU转入风险

国家自然科学基金镇江市重点研发-社会发展项目江苏大学附属医院新冠病毒感染科研专项基金

82202389SH2022095Jdfyxgzx001

2023

中华卫生应急电子杂志

中华卫生应急电子杂志

ISSN:
年,卷(期):2023.9(2)
  • 23