Objective To investigate the predictive value of cardiopulmonary exercise test(CPET)indexes for major adverse cardiovascular events(MACE)in patients with coronary heart disease(CHD).Methods This study was a retrospective cohort study.CHD patients were consecutively enrolled who procedure CPET before discharge from the Department of Cardiology,General Hospital of Northern Theater Command from November 2015 to September 2021 were enrolled.Demographic information,past medical history,CPET indexes and other baseline data were collected and the patients were followed up.Patients were divided into a MACE group and a control group according to the presence or absence of MACE.A multivariate Cox proportional hazard regression model was used to analyze the CPET indexes with predictive value for MACE in CHD patients.Results A total of 3 800 patients were eligible for the criterion,age(57.2±8.8)years,2 920(76.84％)males.During a follow-up of 1 237(695,1 596)days,390(10.26％)patients were in MACE group,and 3 410(89.74％)patients were in control group.In adjusted multivariable analysis,higher metabolic equivalent of tasks(MET)at anaerobic threshold(AT)is an independent protective factor for MACE in patients with CHD(HR=0.75,95％CI 0.62-0.90,P=0.002),higher VE/VCO2 is an independent risk factor for MACE in CHD patients(HR=1.05,95％CI 1.02-1.07,P=0.001).Conclusion In CPET,high MET at AT is an independent protective factor for MACE in patients with CHD,and high VE/VCO2 is an independent risk factor for MACE in CHD patients.
NETL
NSTL
万方数据
