Objective To assess the trends in case-fatality rates for acute myocardial infarction(AMI)in China from 2015 to 2019.Methods This study employed a population-based surveillance.Data from the China Registry of Acute Cardiovascular Event(China RACE)were utilized,including AMI cases reported by Grade Ⅱ and Grade Ⅲ hospitals at the disease surveillance sites across China from January 1st 2015 to December 31st 2019.The 28-day mortality outcome for reported AMI events was obtained by linking to the national death certificate registry system.The study analyzed the overall and age-standardized case-fatality rates,as well as their annual percent change(APC),during the study period,stratified by gender,age,and region.Results The overall 28-day case fatality rate for AMI was 28.97％(22 532/77 764)from 2015 to 2019.The age-standardized case-fatality rate for AMI declined significantly from 37.53％in 2015 to 18.58％in 2019,with an APC of-14.33％(P=0.018).We observed a signifiicant downward trend in case-fatality rates of AMI in both genders(both P＜0.05).Among males,the case-fatality rate decreased more steeply in younger males compared to elder counterparts.The most marked decreases were seen in males aged＜35 years and 35 to 44 years,with APC of-27.63％(P=0.007)and-22.65％(P=0.004),respectively.In females,we observed a relatively stable decrease in case-fatality across age groups.The age-standardized case-fatality rate of AMI in eastern and central China decreased significantly from 2015 to 2019,with the APC of-19.22％(P=0.006)and-15.62％(P=0.032)respectively.However,the age-standardized case-fatality rate of AMI in western China remained stable(P=0.227).Conclusions The prognosis of AMI has considerably improved from 2015 to 2019 in China,regardless of ages and gender.Inequality in case-fatality rates among geographic regions highlights the need for targeted strategies in AMI prevention in western regions.
NETL
NSTL
万方数据
