摘要
本文回顾了嵌合抗原受体巨噬细胞(chimeric antigen receptor macrophage,CAR-M)疗法的发展历程,探讨了其在恶性血液系统疾病中的应用进展,介绍了 CAR-M相关的临床试验,分析了CAR-M疗法在临床应用中面临的优势与挑战,并对其在未来治疗恶性血液病的应用前景进行了展望.
Abstract
This article reviews the development history of chimeric antigen receptor macrophage(CAR-M)therapy,discusses its application in malignant hematologic diseases,introduces related clinical trials,analyzes the advantages and challenges faced by CAR-M therapy in clinical application,and looks forward to its future use in the treatment of malignant hematologic diseases.
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