首页|利用全血红细胞指数鉴别地中海贫血与缺铁性贫血的研究进展

利用全血红细胞指数鉴别地中海贫血与缺铁性贫血的研究进展

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地中海贫血是一种常染色体隐性遗传病,是由于基因突变或缺失所致红细胞珠蛋白生成障碍而引起的溶血性贫血.缺铁性贫血是由于人体对铁的需求与供给失衡,体内缺铁引起的贫血.两者的实验室表现均为小细胞低色素性贫血,但治疗方案完全不同,单从血常规结果上不易将二者鉴别.利用红细胞指数建立公式或模型鉴别诊断二者,早筛查、早诊断、早治疗,预防重度贫血的发生,可为地中海贫血与缺铁性贫血预防提供科学依据.本文将阐述利用红细胞指数鉴别地中海贫血与缺铁性贫血的研究进展.
Research progress on differential diagnosis of thalassemia trait and iron deficiency anemia by blood erythrocyte parameters
Thalassemia trait is an autosomal recessive genetic disease,which is a hemolytic anemia caused by disturbance of erythrocyte hemoglobin production caused by gene mutation or deletion.Iron deficiency anemia is caused by a lack of iron in the body due to an imbalance between the demand and supply of iron.The laboratory manifestations of both are microcytic hypochromic anemia,but the treatment schemes are completely different,and it is difficult to distinguish them from the results of blood count.Erythrocyte parameters can be used to establish a formula or model to differentiate them,which can achieve the purpose of early screening,early diagnosis and early treatment,preventing the occurrence of severe anemia and providing a scientific basis for the thalassemia and iron deficiency anemia prevention.This article will review the research progress of using erythrocyte parameters to distinguish thalassemia trait with iron deficiency anemia.

Thalassemia traitIron deficiency anemiaErythrocyte parametersDifferential diagnosis

崔丽霞、纪玲

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汕头大学医学院临床检验诊断学系,汕头 515100

北京大学深圳医院检验科,深圳 518000

地中海贫血 缺铁性贫血 红细胞指数 鉴别诊断

2024

中华预防医学杂志
中华医学会

中华预防医学杂志

CSTPCD北大核心
影响因子:1.652
ISSN:0253-9624
年,卷(期):2024.58(1)
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