Rapid and accurate diagnostic technologies are crucial for early detection and diagnosis of diseases.Electrowetting-on-dielectric digital microfluidics,with its high-precision detection and high-throughput screening capabilities,significantly enhances the accuracy and efficiency in early disease diagnosis and personalized treatment,enabling swift disease detection and widespread screening.This article provides a comprehensive review of the working principles and fabrication processes of digital microfluidic chips based on electrowetting on dielectric method.It details the latest research progress in the areas of nucleic acids,proteins,and cells,organizes the commercialization of digital microfluidics technology,and finally discusses the current challenges and future directions of digital microfluidic chips.
关键词
数字微流控芯片技术/介电润湿/疾病预防/临床应用
Key words
Digital microfluidic chip/Electrowetting on dielectric/Disease prevention/Clinical application
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