中华眼科医学杂志(电子版)2023,Vol.13Issue(1) :40-44.DOI:10.3877/cma.j.issn.2095-2007.2023.01.008

幼年特发性关节炎相关葡萄膜炎的研究进展

Research progress of uveitis associated with juvenile idiopathic arthritis

李文捷 卢弘
中华眼科医学杂志(电子版)2023,Vol.13Issue(1) :40-44.DOI:10.3877/cma.j.issn.2095-2007.2023.01.008

幼年特发性关节炎相关葡萄膜炎的研究进展

Research progress of uveitis associated with juvenile idiopathic arthritis

李文捷 1卢弘2
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作者信息

  • 1. 730000 兰州大学第一临床医学院2019级博士研究生;730000 兰州大学第一医院眼科
  • 2. 730000 兰州大学第一医院眼科;100020 首都医科大学附属北京朝阳医院眼科
  • 折叠

摘要

幼年特发性关节炎相关葡萄膜炎(JIA-U)是幼年特发性关节炎(JIA)常见的关节外表现。JIA-U通常表现为慢性前葡萄膜炎,发病隐匿,常伴随威胁视力的并发症。JIA-U治疗主要为控制JIA-U眼内炎症至无或最小活动态,并保持其静止,从而避免多种并发症的发生。了解JIA-U的发病机制和相关危险因素,可有利于及时治疗和最大程度地降低患者的视力损害程度。因此,本文中笔者现就JIA-U的流行特点、发病机制、临床表现、诊断及治疗进展进行综述。

Abstract

Juvenile idiopathic arthritis associated uveitis (JIA-U) is the most common extra-articular manifestation of juvenile idiopathic arthritis (JIA). JIA-U usually is characterized by chronic anterior uveitis, with insidious onset and often companying with vision-threatening complications. The goal of treatment for JIA-U is to reduce intraocular inflammation to zero or minimal activity to maintain immobility, which to be avoided various kinds of complications of JIA-U. It is of great benefit for ophthalmologists to understand the pathogenesis of JIA-U and associated risk factors, which to timely treat and reduce visual impairment with the greatest degree of effort. Therefore, the epidemic characteristics, pathogenesis, clinical manifestations, diagnosis and treatment of JIA-U were reviewed in this paper.

关键词

幼年特发性关节炎相关葡萄膜炎/发病机制/定期筛查/诊断/治疗

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基金项目

甘肃省自然科学基金(17JR5RA225)

甘肃省高等学校创新基金(2021B-023)

出版年

2023
中华眼科医学杂志(电子版)

中华眼科医学杂志(电子版)

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