摘要
圆锥角膜是一种进行性扩张性角膜病变，多在青春期发病，以角膜膨隆变薄、不规则散光为主要特征。当前，角膜胶原交联术已成为治疗进展期圆锥角膜的主要手段。与成人相比，儿童圆锥角膜进展更快、病情更重，更应及早发现、尽早治疗。本综述旨在介绍儿童圆锥角膜的流行病学与发病机制以及儿童行角膜胶原交联术(CXL)的适应证、不同手术方式、手术疗效和术后随访等新发现与新进展。
Abstract
Corneal keratoconus is a progressive dilated keratopathy that often occurs during adolescence, characterized by corneal dilation and thinning, as well as irregular astigmatism. Currently, corneal collagen cross-linking has become the main method for treating advanced keratoconus. Compared with adults with keratoconus, pediatric keratoconus have shown a faster progress and worse condition, which should be detected and treated as soon as possible. The epidemiology and pathogenesis of keratoconus in children, as well as new findings and developments in the indications, different surgical methods, surgical efficacy, and postoperative follow-up of corneal collagen cross-linking surgery (CXL) in children were reviewed in this paper.
基金项目
首都卫生发展科研专项基金(首发2018-2-4092)
万方数据