摘要
不编码蛋白质的核糖核酸(RNA)称为非编码RNA。其中，调控性非编码RNA主要包括微小RNA(miRNA)、长链非编码RNA(lncRNA)和环状RNA(circRNA)。非编码RNA在细胞生长、增殖、分化、凋亡和氧化应激等多种生物学过程中发挥关键作用。近年来，有许多研究发现非编码RNA在白内障的发生与发展中发挥了调控作用，可能成为非手术治疗而具有应用前景的新靶点。本文中笔者就近年来国内外非编码RNA与白内障的相关研究进展进行综述。
Abstract
Ribonucleic acid (RNA) that does not encode proteins is called non coding RNA. Among them, regulatory non coding RNA mainly includes microRNA (miRNA), long chain non coding RNA (lncRNA) and circular RNA (circRNA). Non coding RNA plays a crucial role in various biological processes such as cell growth, proliferation, differentiation, apoptosis, and oxidative stress. In recent years, it has been demonstrated that non coding RNA plays an important regulatory role in the occurrence and development of cataracts, and may become a promising new target for non-surgical treatment. In this paper, the research progress on non coding RNA and cataract in recent years both domestically and internationally were reviewed.
万方数据