摘要
老视是指因年龄增长所致的不可逆性生理性调节减弱，并严重影响患者视觉质量的现象。未经恰当矫正的老视是全球人口视力受损的首要因素。近年来，框架眼镜、手术及角膜接触镜等传统矫正方案已不能满足老视人群日益增长的需求，药物治疗老视可能是其新方案。本文中笔者对老视药物的应用现状和发展策略进行综述，旨在比较现有药物的有效性与安全性，并提出未来新药开发的潜在方向。
Abstract
Presbyopia is the irreversible loss of the accommodative ability of the eye that occurs due to ageing, which severely affects patients′ visual quality. Globally, presbyopia without proper correction is the primary cause of visual impairment. Despite widespread use of glasses, surgery and contact lens, there has been an increasing demand for novel treatment strategies. Recently, the pharmacological treatments for presbyopia provide an alternative strategy. The current status and evolving strategies of pharmacological approaches to the treatment of presbyopia were reviewed, aiming to compare the safety and efficiency of current therapies and put forward potential drug candidates.
基金项目
广西医疗卫生适宜技术开发与推广应用项目(S2020077)
万方数据