摘要
角膜或巩膜干凹斑是因泪膜分布异常、局部组织干燥脱水引起的角膜缘或巩膜裸露部位的碟形凹陷。有研究结果表明，干凹斑可见于翼状胬肉术后、斜视术后、青光眼大滤过泡、巩膜炎、结膜高度水肿及Graves眼病。患者可无任何不适或仅有轻度异物感。常规治疗方法有眼表润滑药物、人工泪液、加压包眼以及配戴角膜绷带镜等。经局部水化治疗后，干凹斑多数可较快修复；治疗不及时则会发展为组织溃疡和穿孔等严重并发症。
Abstract
Corneal or scleral dellen are small saucer-like excavations in the corneal periphery or bare sclera, which caused by interruptions of the tear film and local dehydration of tissues. It has been demonstrated that dellen formation was associated with pterygium surgery, strabismus surgery, large filtration blebs, scleritis, severe conjunctival chemosis, Graves′s eye disease, etc. Patients can have no discomfort or only complaints about foreign body sensation and mild discomfort. Conventional treatment approaches include lubrication, artificial tears, patching, and wearing bandage contact lens. The corneoscleral dellen rapidly has been improved after topical hydration therapy with tear-film. The dellen may lead to corneal or scleral perforation, causing serious complications if not discovered and treated in timely.
基金项目
山东省医药卫生科技发展计划项目(2019WS569)
山东省医药卫生科技发展计划项目(202007020916)
万方数据