维生素D与眼病关系的研究进展
Advances on the vitamin D and ocular disease
李新星 1方晏红 1陈会振 1张蓝月 1刘涵1
作者信息
- 1. 402260 重庆大学附属江津医院眼科
- 折叠
摘要
维生素D是一种类固醇激素,在生理学中具有多种作用,包括维持钙稳态、调节免疫、促进细胞分化和增殖.维生素D在干眼、糖尿病视网膜病变(DR)及甲状腺相关性眼病中的作用已经得到了广泛证实.既往研究结果表明,维生素D与包括近视眼、年龄相关性黄斑变性(AMD)、青光眼、DR、干眼、甲状腺相关性眼病,葡萄膜炎、视网膜母细胞瘤及白内障等眼病疾病均相关.本文中笔者从维生素D代谢角度探讨维生素D与眼病疾病的相关性,旨在为眼部疾病诊治提供新思路.
Abstract
Vitamin D is a steroid hormone that has widespread role in human physiology,not only in the maintenance of calcium homeostasis but also in immunomodulation,cellular differentiation,and proliferation.The role of vitamin D in ocular surface conditions such as dry eye disease,diabetic retinopathy,and thyroid eye disease has received widespread and well deserved attention.It has been demonstrated that vitamin D has associated with eye diseases including myopia,age-related macular degeneration(AMD),glaucoma,DR,dry eye,thyroid related eye diseases,uveitis,retinoblastoma,and cataracts.The correlation between vitamin D and eye diseases from the perspective of vitamin D metabolism was reviewed,aiming to provide new ideas for the diagnosis and treatment of eye diseases.
关键词
维生素D/糖尿病视网膜病变/干眼/近视眼/年龄相关性黄斑变性/甲状腺相关性眼病Key words
Vitamin D/Diabetic retinopathy/Dry eye syndrome/Myopia/Age-related macular degeneration/Thyroid eye disease引用本文复制引用
基金项目
2020年重庆市自然科学基金项目(cstc2020jcyjmsxmX0698)
2023年重庆市自然科学基金项目(CSTB2023NSCQ-MSX0639)
2023年重庆市江津区科学技术局项目(Y2023016)
出版年
2023
NETL
NSTL
万方数据