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检验医学与生命组学协同发展的机遇和挑战

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随着蛋白质组学技术日趋成熟,近年来蛋白质组学在重大疾病的早期检测、疾病分型和药靶发现等领域不断取得重要成果。为深入探讨以蛋白质组学为主的前沿生命组学技术在推动精准检验医学发展中的重要作用和在创新成果临床转化过程中面临的机遇和挑战,国家蛋白质科学中心(北京)邀请来自检验医学、生命组学和精准医疗的知名专家学者,围绕检验医学与生命组学协同发展、临床检验新技术的未来趋势、生命组学对于检验医学的创新和发展、蛋白质组学技术在检验医学中的转化应用和蛋白质组学成果产业化的机遇和挑战等议题分享他们对生命组学技术和成果在检验医学中的经验和看法。大家一致认为蛋白质组学为疾病的精准诊疗提供了新的方向和机遇,但还需产学研紧密合作,同时要解决设备临床适用性、检测方法和数据标准化、成本和质量控制、人才培养和产业化路径等问题。 With the maturation of proteomics technologies in recent years, proteomics has made significant achievements in early detection of major diseases, disease classification, drug target discovery, and other fields. To explore the important role of proteomics, especially proteomics-based cutting-edge lifeomics technologies, in promoting the development of precision laboratory medicine and to discuss the opportunities and challenges faced during the clinical translation of innovative outcomes, the National Center for Protein Sciences-Beijing invited renowned experts and scholars in laboratory medicine, lifeomics, and precision medicine. The discussions revolved around the collaborative development of laboratory medicine and lifeomics, the future trends of new technologies in clinical laboratory testing, the innovation and development of lifeomics in laboratory medicine, the translational application of proteomics technologies in laboratory medicine, and the opportunities and challenges in the industrialization of proteomics achievements. All participants agreed that proteomics provides new directions and opportunities for precision diagnosis and treatment of diseases. However, close collaboration between academia, hospitals and industry is required. Additionally, challenges such as clinical applicability of equipment, standardization of detection methods and data, cost and quality control, talent cultivation, and the industrialization pathway need to be addressed.
Opportunities and challenges in the collaborative development of laboratory medicine and lifeomics
With the maturation of proteomics technologies in recent years, proteomics has made significant achievements in early detection of major diseases, disease classification, drug target discovery, and other fields. To explore the important role of proteomics, especially proteomics-based cutting-edge lifeomics technologies, in promoting the development of precision laboratory medicine and to discuss the opportunities and challenges faced during the clinical translation of innovative outcomes, the National Center for Protein Sciences-Beijing invited renowned experts and scholars in laboratory medicine, lifeomics, and precision medicine. The discussions revolved around the collaborative development of laboratory medicine and lifeomics, the future trends of new technologies in clinical laboratory testing, the innovation and development of lifeomics in laboratory medicine, the translational application of proteomics technologies in laboratory medicine, and the opportunities and challenges in the industrialization of proteomics achievements. All participants agreed that proteomics provides new directions and opportunities for precision diagnosis and treatment of diseases. However, close collaboration between academia, hospitals and industry is required. Additionally, challenges such as clinical applicability of equipment, standardization of detection methods and data, cost and quality control, talent cultivation, and the industrialization pathway need to be addressed.

Laboratory medicineLifeomicsProteomics

于晓波、孙爱华、王琰、贺福初、干岭

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医学蛋白质组国家重点实验室 国家蛋白质科学中心-北京(凤凰中心)北京生命组学研究所 北京蛋白质组研究中心,北京 102206

检验医学 生命组学 蛋白质组学

战略性国际科技创新合作重点专项

2020YFE0202200

2024

中华检验医学杂志
中华医学会

中华检验医学杂志

CSTPCD北大核心
影响因子:1.402
ISSN:1009-9158
年,卷(期):2024.47(1)