The clinical value of RNA methylation modification as novel tumor molecular diagnostic biomarkers
Malignant tumors have become the main threaten of human health,however,highly sensitive and specific diagnostic biomarkers and effective therapeutic targets are still lacking for most cancers currently.RNA methylation modification has been a cutting-edge hotspot in RNA research area in recent years.The dynamic changes of RNA methylation patterns and levels in tumor tissues,cells as well as patients'peripheral blood are closely associated with tumor occurrence,development,and prognosis,and have the potential to serve as precise diagnostic markers and effective therapeutic targets for tumors.Even though several challenges such as RNA methylation detection methods,functional mechanism,and the development of therapeutic drugs based on RNA methylation modification are needed to solve,from lab to clinical practice,RNA methylation still display excellent diagnostic and prognosis performance,which can provide new strategies and evidence for precise diagnosis,treatment targets,and drug development of tumors.
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维普
