Clinical application progress of flow cytometry in diagnosis and therapeutic monitoring of patients with nonhematopoietic neoplasms
Flow cytometry(FCM)is an interdisciplinary cell analysis technology that integrates optics,fluid dynamics,electronics,and computer science.While FCM is widely utilized in diagnosing and monitoring hematologic malignancies,its application in nonhematopoietic neoplasms(NHN)remains in its nascent stages.However,recent advancements in science and technology have led to the emergence of innovative FCM technologies,such as mass spectrometry flow cytometry(CyTOF)and spectral flow cytometry(SFC),offering promising avenues for their clinical application aiming to assist the clinical diagnosis of NHN patients.This review summarizes the features of fundamentals of traditional FCM,CyTOF,and SFC technologies,along with their applications and future prospective in NHN diagnosis and treatment,aiming to offer updated insights for the continued expansion and utilization of FCM technology in clinical laboratory settings.
万方数据
维普
