首页|骨髓增生异常综合征/肿瘤和急性髓系白血病WHO分类和国际共识分类比较

骨髓增生异常综合征/肿瘤和急性髓系白血病WHO分类和国际共识分类比较

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世界卫生组织(WHO)有关造血与淋巴组织肿瘤的国际诊断和分类标准(WHO-HEAM)自2001年以来,经历了多个版本的升级和修订,对先前一些肿瘤的诊断和分类标准进行了更新、澄清和细化,同时增加了许多新的遗传学和分子生物学亚型.由于大量临床和科学研究结果的出现以及专家对诊断分类的分歧,2022年出现了两个分类建议,即2022年Leukemia杂志上发布的第5版WHO造血与淋巴组织分类(WHO-HAEM5)和Blood杂志上发表的国际共识分类(ICC).这两个方案对造血与淋巴组织肿瘤的分类有所不同,给临床实验室诊断和治疗带来了一些困扰和挑战.
Comparison the WHO classification and the International Consensus Classification for myelodysplastic syndromes/neoplasms and acute myeloid leukemia
The World Health Organization(WHO)classification serves as the internationally recognized standard for diagnosing and classifying hematopoietic and lymphoid tissue tumors(WHO-HEAM).Since 2001,it has undergone multiple upgrades and revisions,updating,clarifying,and refining previous tumor diagnostic and classification standards while incorporating numerous new genetic and molecular biological subtypes.In 2022,two classification proposals emerged due to a wealth of clinical and scientific research results:the fifth edition of the WHO hematopoietic and lymphoid tissue classification(WHO-HAEM5),published in Leukemia journal;and the International Consensus Classification(ICC),published in Blood journal.These two schemes differ in their approach to classifying hematopoietic and lymphoid tissue tumors,posing challenges for clinical laboratory diagnosis and treatment.

Hematologic neoplasmsLeukemiaWHO classification of hematopoietic and lymphoid tissue neoplasmsInternational Consensus ClassificationMyelodysplastic syndromes/neoplasmsAcute myeloid leukemia

刘义刚、曲惠廷、李丽、王晶、房孝生、王倩、王子娥、孙慧、黄敏、张健、张之芬、甄晓玲、赵文博、武焕玲

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山东第一医科大学附属省立医院临床医学检验部,济南 250021

山东第一医科大学附属省立医院血液内科,济南 250021

青岛市立医院检验科,青岛 266000

血液肿瘤 白血病 WHO造血与淋巴组织肿瘤分类 国际共识分类 骨髓增生异常综合征肿瘤 急性髓系白血病

山东第一医科大学附属省立医院横向科研项目

HXKT0010

2024

中华检验医学杂志
中华医学会

中华检验医学杂志

CSTPCD北大核心
影响因子:1.402
ISSN:1009-9158
年,卷(期):2024.47(8)